Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965556 | 1.00 | EDNRA (0.67) | EDNRAEDNRB | |
| SCHEMBL7334926 | 0.83 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL6151590 | 0.83 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL6151094 | 0.83 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL4630677 | 0.82 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL6151441 | 0.82 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL4631538 | 0.81 | EDNRA (0.83) | EDNRAEDNRB | |
| SCHEMBL6150975 | 0.81 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6151346 | 0.80 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL6150917 | 0.80 | EDNRA (0.73) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819125-A1 | THIENYL-, FURYL-, PYRROLYL- AND BIPHENYLSULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996031492-A1 | THIENYL-, FURYL-, PYRROLYL- AND BIPHENYLSULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1996-10-10 | — | — | WO | disclosed |