Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PREP | P48147 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345803 | 1.00 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2PREPNPSR1 | |
| SCHEMBL2760309 | 1.00 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2PREPNPSR1 | |
| SCHEMBL7345795 | 1.00 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2PREPNPSR1 | |
| SCHEMBL2760307 | 0.89 | PREP (0.52) | NPC1RAB9ASMN1; SMN2PREPNPSR1 | |
| SCHEMBL13507486 | 0.88 | SMN1; SMN2 (0.54) | NPC1RAB9ASMN1; SMN2PREPNPSR1 | |
| SCHEMBL6121679 | 0.87 | POLB (0.53) | NPC1RAB9ASMN1; SMN2PREP | |
| SCHEMBL29302474 | 0.87 | POLB (0.53) | NPC1RAB9ASMN1; SMN2PREP | |
| SCHEMBL26777858 | 0.87 | POLB (0.53) | NPC1RAB9ASMN1; SMN2PREP | |
| SCHEMBL6121682 | 0.87 | POLB (0.53) | NPC1RAB9ASMN1; SMN2PREP | |
| SCHEMBL4668774 | 0.86 | SMN1; SMN2 (0.61) | NPC1RAB9ASMN1; SMN2PREPNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371091-A | Anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-12-06 | — | — | US | disclosed |