Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 11/20 | 0.80 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.80 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.80 |
| ▸ | PDE4A | P27815 | 6/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338128 | 1.00 | PDE4D (0.80) | PDE4DPDE4BMAPK14PDE4APDE4C | |
| SCHEMBL14457690 | 0.90 | PDE4D (0.84) | PDE4DPDE4BMAPK14PDE4APDE4C | |
| Filaminast SCHEMBL29412441 | 0.89 | PDE4D (1.00) | PDE4DPDE4BMAPK14PDE4APDE4C | |
| Filaminast SCHEMBL73844 | 0.89 | PDE4D (1.00) | PDE4DPDE4BMAPK14PDE4APDE4C | |
| Filaminast SCHEMBL13986144 | 0.89 | PDE4D (1.00) | PDE4DPDE4BMAPK14PDE4APDE4C | |
| Filaminast SCHEMBL73843 | 0.89 | PDE4D (1.00) | PDE4DPDE4BMAPK14PDE4APDE4C | |
| SCHEMBL7341873 | 0.88 | PDE4D (0.77) | PDE4DPDE4BMAPK14PDE4APDE4C | |
| SCHEMBL7341870 | 0.88 | PDE4D (0.77) | PDE4DPDE4BMAPK14PDE4APDE4C | |
| SCHEMBL4452797 | 0.82 | PDE4B (0.67) | PDE4DPDE4BMAPK14PDE4APDE4C | |
| SCHEMBL29824899 | 0.82 | PDE4B (0.67) | PDE4DPDE4BMAPK14PDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470805-B1 | Oxime-carbamates and oxime-carbonates as bronchodilators and anti-inflammatory agents | AMERICAN HOME PROD (US) | 1994-09-07 | — | — | EP | claimed |
| EP-0470805-A1 | Oxime-carbamates and oxime-carbonates as bronchodilators and anti-inflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-02-12 | — | — | EP | claimed |