Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 9/20 | 0.63 |
| ▸ | YAP1 | P46937 | 3/20 | 0.57 |
| ▸ | PSMB11 | A5LHX3 | 5/20 | 0.56 |
| ▸ | PSMA7 | O14818 | 5/20 | 0.56 |
| ▸ | PSMB1 | P20618 | 5/20 | 0.56 |
| ▸ | PSMA1 | P25786 | 5/20 | 0.56 |
| ▸ | PSMA2 | P25787 | 5/20 | 0.56 |
| ▸ | PSMA3 | P25788 | 5/20 | 0.56 |
| ▸ | PSMA4 | P25789 | 5/20 | 0.56 |
| ▸ | PSMB8 | P28062 | 5/20 | 0.56 |
| ▸ | PSMB9 | P28065 | 5/20 | 0.56 |
| ▸ | PSMA5 | P28066 | 5/20 | 0.56 |
| ▸ | PSMB4 | P28070 | 5/20 | 0.56 |
| ▸ | PSMB6 | P28072 | 5/20 | 0.56 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.56 |
| ▸ | PSMB10 | P40306 | 5/20 | 0.56 |
| ▸ | PSMB3 | P49720 | 5/20 | 0.56 |
| ▸ | PSMB2 | P49721 | 5/20 | 0.56 |
| ▸ | PSMA6 | P60900 | 5/20 | 0.56 |
| ▸ | PSMA8 | Q8TAA3 | 5/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347454 | 0.97 | CACNA1B (0.62) | CACNA1BYAP1PSMB11PSMA7PSMB1 | |
| SCHEMBL7339387 | 0.94 | CACNA1B (0.60) | CACNA1BYAP1PSMB11PSMA7PSMB1 | |
| SCHEMBL7337669 | 0.92 | CACNA1B (0.58) | CACNA1BYAP1PSMB11PSMA7PSMB1 | |
| SCHEMBL7346412 | 0.91 | CACNA1B (0.59) | CACNA1BYAP1PSMB11PSMA7PSMB1 | |
| SCHEMBL7339685 | 0.90 | CACNA1B (0.56) | CACNA1BPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL7339830 | 0.89 | CACNA1B (0.68) | CACNA1BYAP1PSMB11PSMA7PSMB1 | |
| SCHEMBL7343211 | 0.88 | CACNA1B (0.59) | CACNA1BYAP1PSMB11PSMA7PSMB1 | |
| SCHEMBL7338008 | 0.88 | CACNA1B (0.59) | CACNA1BYAP1PSMB11PSMA7PSMB1 | |
| SCHEMBL7341876 | 0.88 | CACNA1B (0.61) | CACNA1BPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL7343475 | 0.88 | IL1RN (0.62) | CACNA1BYAP1PSMB11PSMA7PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |