Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 4/20 | 0.56 |
| ▸ | PSMB2 | P49721 | 11/20 | 0.53 |
| ▸ | PSMB8 | P28062 | 10/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 10/20 | 0.53 |
| ▸ | PSMB10 | P40306 | 10/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 9/20 | 0.53 |
| ▸ | PSMB9 | P28065 | 9/20 | 0.53 |
| ▸ | PSMB11 | A5LHX3 | 8/20 | 0.53 |
| ▸ | PSMA7 | O14818 | 8/20 | 0.53 |
| ▸ | PSMA1 | P25786 | 8/20 | 0.53 |
| ▸ | PSMA2 | P25787 | 8/20 | 0.53 |
| ▸ | PSMA3 | P25788 | 8/20 | 0.53 |
| ▸ | PSMA4 | P25789 | 8/20 | 0.53 |
| ▸ | PSMA5 | P28066 | 8/20 | 0.53 |
| ▸ | PSMB4 | P28070 | 8/20 | 0.53 |
| ▸ | PSMB6 | P28072 | 8/20 | 0.53 |
| ▸ | PSMB3 | P49720 | 8/20 | 0.53 |
| ▸ | PSMA6 | P60900 | 8/20 | 0.53 |
| ▸ | PSMA8 | Q8TAA3 | 8/20 | 0.53 |
| ▸ | PSMB7 | Q99436 | 8/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345978 | 0.94 | CACNA1B (0.56) | CACNA1BPSMB2PSMB8PSMB5PSMB10 | |
| SCHEMBL7345058 | 0.91 | CACNA1B (0.51) | CACNA1BPSMB2PSMB8PSMB5PSMB10 | |
| SCHEMBL7337022 | 0.90 | CACNA1B (0.53) | CACNA1BPSMB2PSMB8PSMB5PSMB10 | |
| SCHEMBL7341833 | 0.90 | CACNA1B (0.62) | CACNA1BPSMB2PSMB8PSMB5PSMB10 | |
| SCHEMBL7339756 | 0.90 | CACNA1B (0.54) | CACNA1BPSMB2PSMB8PSMB5PSMB10 | |
| SCHEMBL7345205 | 0.90 | CACNA1B (0.54) | CACNA1BPSMB2PSMB8PSMB5PSMB10 | |
| SCHEMBL7345670 | 0.90 | CACNA1B (0.49) | CACNA1BPSMB2PSMB8PSMB5PSMB10 | |
| SCHEMBL7346889 | 0.89 | CACNA1B (0.56) | CACNA1BPSMB2PSMB8PSMB5PSMB10 | |
| SCHEMBL7348732 | 0.89 | CACNA1B (0.51) | CACNA1BPSMB2PSMB8PSMB5PSMB10 | |
| SCHEMBL7337684 | 0.89 | CACNA1B (0.51) | CACNA1BPSMB2PSMB8PSMB5PSMB10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |