Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.34 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7780856 | 0.99 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BTP53GAA | |
| SCHEMBL7338630 | 0.92 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BTP53GAA | |
| Hydrochloric Acid SCHEMBL7780840 | 0.91 | AVPR2 (0.45) | AVPR2AVPR1AAVPR1BTP53GAA | |
| SCHEMBL7338527 | 0.89 | AVPR2 (0.36) | AVPR2AVPR1AAVPR1BGAASMN1; SMN2 | |
| SCHEMBL7340696 | 0.89 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BTP53GAA | |
| Hydrochloric Acid SCHEMBL7778262 | 0.89 | AVPR2 (0.35) | AVPR2AVPR1AAVPR1BGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7341534 | 0.88 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BTP53GAA | |
| SCHEMBL7780645 | 0.87 | AVPR2 (0.41) | AVPR2AVPR1AAVPR1BTP53GAA | |
| SCHEMBL7338684 | 0.86 | AVPR2 (0.38) | AVPR2AVPR1AAVPR1BTP53GAA | |
| Hydrochloric Acid SCHEMBL7780587 | 0.86 | AVPR2 (0.41) | AVPR2AVPR1AAVPR1BTP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |