Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 9/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.52 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.49 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.49 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.49 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.49 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.49 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.49 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.49 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339830 | 0.94 | CACNA1B (0.68) | CACNA1BPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL7339860 | 0.93 | CACNA1B (0.66) | CACNA1BCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7343050 | 0.93 | CACNA1B (0.65) | CACNA1BCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7342221 | 0.93 | CACNA1B (0.67) | CACNA1BPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL7345374 | 0.92 | CACNA1B (0.66) | CACNA1BPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL7407724 | 0.90 | CACNA1B (0.54) | CACNA1BCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7339693 | 0.89 | CACNA1B (0.62) | CACNA1BPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL7345737 | 0.89 | CACNA1B (0.62) | CACNA1BPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL7339817 | 0.89 | CACNA1B (0.62) | CACNA1BPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL7340496 | 0.89 | CACNA1B (0.61) | CACNA1BPSMB11PSMA7PSMB1PSMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |