Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.38 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PNLIP | P16233 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7342240 | 0.91 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1BLMNAHTT | |
| SCHEMBL7345595 | 0.87 | RXFP1 (0.34) | AVPR2AVPR1AAVPR1BKDM4ERXFP1 | |
| SCHEMBL7336955 | 0.85 | AVPR2 (0.40) | AVPR2AVPR1AAVPR1BRAB9ASMN1; SMN2 | |
| SCHEMBL7778279 | 0.85 | AVPR2 (0.47) | AVPR2AVPR1AAVPR1BRAB9ASMN1; SMN2 | |
| SCHEMBL7335858 | 0.85 | AVPR2 (0.44) | AVPR2AVPR1AAVPR1BRAB9ALMNA | |
| SCHEMBL7340008 | 0.80 | CYP19A1 (0.40) | AVPR2AVPR1AAVPR1BMEN1KMT2A | |
| SCHEMBL7338630 | 0.78 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BLMNAHTT | |
| SCHEMBL7340679 | 0.78 | AVPR2 (0.49) | AVPR2AVPR1AAVPR1BRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7375753 | 0.78 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7780840 | 0.78 | AVPR2 (0.45) | AVPR2AVPR1AAVPR1BLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |