Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 7/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.42 |
| ▸ | AVPR1B | P47901 | 6/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345366 | 0.94 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BTP53GAA | |
| SCHEMBL7336166 | 0.93 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BBRPF1BRD4 | |
| SCHEMBL7336265 | 0.93 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BBRPF1BRD4 | |
| Hydrochloric Acid SCHEMBL7335182 | 0.93 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BBRPF1BRD4 | |
| SCHEMBL7343158 | 0.93 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BRXFP1BRPF1 | |
| SCHEMBL7343561 | 0.93 | AVPR2 (0.43) | AVPR2AVPR1AAVPR1BTP53GAA | |
| Hydrochloric Acid SCHEMBL7773784 | 0.93 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BBRPF1BRD4 | |
| Hydrochloric Acid SCHEMBL7345642 | 0.93 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BBRPF1BRD4 | |
| Hydrochloric Acid SCHEMBL7780759 | 0.92 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BRXFP1BRPF1 | |
| SCHEMBL7342173 | 0.92 | AVPR2 (0.43) | AVPR2AVPR1AAVPR1BBRPF1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |