Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339357 | 1.00 | SRD5A1 (0.45) | SRD5A1HTR2CHTR2BNOTUMHSD17B10 | |
| SCHEMBL7346061 | 1.00 | SRD5A1 (0.45) | SRD5A1HTR2CHTR2BNOTUMHSD17B10 | |
| SCHEMBL7338761 | 0.83 | SRD5A1 (0.42) | SRD5A1HTR2CHTR2BNOTUMCYP19A1 | |
| SCHEMBL7340163 | 0.83 | SRD5A1 (0.42) | SRD5A1HTR2CHTR2BNOTUMHSD17B10 | |
| SCHEMBL7337574 | 0.83 | SRD5A1 (0.42) | SRD5A1HTR2CHTR2BNOTUMCYP19A1 | |
| SCHEMBL7337570 | 0.83 | SRD5A1 (0.42) | SRD5A1HTR2CHTR2BNOTUMCYP19A1 | |
| SCHEMBL7340157 | 0.83 | SRD5A1 (0.42) | SRD5A1HTR2CHTR2BNOTUMHSD17B10 | |
| SCHEMBL7343695 | 0.83 | SRD5A1 (0.42) | SRD5A1HTR2CHTR2BNOTUMHSD17B10 | |
| SCHEMBL7341774 | 0.82 | SRD5A1 (0.39) | SRD5A1TSHRPDK1PDK2PDK3 | |
| SCHEMBL7341785 | 0.82 | SRD5A1 (0.39) | SRD5A1TSHRPDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699680-B1 | Oxazoloquinolinone derivatives, their preparation and their use in therapy | SANOFI SYNTHELABO (FR) | 2000-03-08 | — | — | EP | disclosed |
| US-5641785-A | ANTIDEPRESSANTS, NERVOUS SYSTEM DISORDERS | SYNTHELABO (FR) | 1997-06-24 | — | — | US | disclosed |