Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 2/20 | 0.64 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334632 | 0.83 | TNKS (0.74) | TNKS | |
| SCHEMBL7332529 | 0.83 | TNKS (0.74) | TNKS | |
| SCHEMBL7327517 | 0.80 | TNKS (0.65) | TNKS | |
| SCHEMBL7339375 | 0.79 | TNKS (0.71) | TNKS | |
| SCHEMBL7336678 | 0.78 | TNKS (0.74) | TNKS | |
| SCHEMBL7338405 | 0.78 | TNKS (1.00) | TNKS | |
| SCHEMBL7337736 | 0.77 | TNKS (0.73) | TNKS | |
| SCHEMBL7335365 | 0.75 | TNKS (0.58) | TNKS | |
| SCHEMBL7330999 | 0.75 | TNKS (0.55) | TNKS | |
| SCHEMBL7334732 | 0.75 | TNKS (0.69) | TNKSMAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726900-A1 | 7H-IMIDAZO(1,2-a)PYRAZINE-8-ONE NMDA RECEPTOR ANTAGONISTS | Aventis Pharma S.A. (FR) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012594-A1 | 7H-IMIDAZO(1,2-a)PYRAZINE-8-ONE NMDA RECEPTOR ANTAGONISTS | RHONE-POULENC RORER S.A. (FR) | 1995-05-11 | — | — | WO | disclosed |