Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 18/20 | 0.75 |
| ▸ | AVPR1A | P37288 | 12/20 | 0.70 |
| ▸ | OXTR | P30559 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335779 | 0.94 | AVPR2 (0.77) | AVPR2AVPR1AOXTR | |
| SCHEMBL7341071 | 0.94 | AVPR2 (0.79) | AVPR2AVPR1AOXTR | |
| SCHEMBL7333369 | 0.93 | AVPR2 (0.69) | AVPR2AVPR1AOXTR | |
| SCHEMBL7341035 | 0.92 | AVPR2 (0.81) | AVPR2AVPR1AOXTR | |
| SCHEMBL7339626 | 0.92 | AVPR2 (0.71) | AVPR2AVPR1AOXTR | |
| SCHEMBL7338509 | 0.91 | AVPR2 (0.68) | AVPR2AVPR1AOXTR | |
| SCHEMBL7334759 | 0.89 | AVPR2 (0.76) | AVPR2AVPR1AOXTR | |
| SCHEMBL6993636 | 0.87 | AVPR2 (0.84) | AVPR2AVPR1AOXTR | |
| SCHEMBL6997117 | 0.86 | AVPR2 (1.00) | AVPR2AVPR1AOXTR | |
| SCHEMBL7341237 | 0.85 | AVPR2 (0.71) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | claimed |
| US-5624923-A | UROGENITAL AND CARDIOVASCULAR DISORDERS | AMERICAN CYANAMID COMPANY (US) | 1997-04-29 | — | — | US | claimed |
| US-5968930-A | FOR TREATMENT AND/OR PREVENTION OF HYPERTENSION, CARDIAC INSUFFICIENCY, CORONARY VASOSPASM, CARDIAC ISCHEMIA, RENAL VASOSPASM, LIVER CIRRHOSIS, CONGESTIVE HEART FAILURE, NEPHROTIC SYNDROME, BRAIN EDEMA, CEREBRAL ISCHEMIA | AMERICAN CYANAMID COMPANY (US) | 1999-10-19 | — | — | US | disclosed |
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |
| US-5624923-A | UROGENITAL AND CARDIOVASCULAR DISORDERS | AMERICAN CYANAMID COMPANY (US) | 1997-04-29 | — | — | US | disclosed |