Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27447205 | 0.87 | CYP1A2 (0.40) | CYP1A2CYP2D6MEN1KMT2ADRD4 | |
| SCHEMBL4105828 | 0.86 | MEN1 (0.37) | CYP1A2CYP2D6MEN1KMT2ADRD4 | |
| SCHEMBL5613182 | 0.82 | CYP1A2 (0.39) | CYP1A2CYP2D6MEN1KMT2ADRD4 | |
| SCHEMBL23902086 | 0.82 | MEN1 (0.39) | CYP1A2CYP2D6MEN1KMT2ADRD4 | |
| SCHEMBL9787947 | 0.81 | MEN1 (0.39) | CYP1A2CYP2D6MEN1KMT2ADRD4 | |
| SCHEMBL4665795 | 0.81 | MEN1 (0.39) | CYP1A2CYP2D6MEN1KMT2ADRD4 | |
| SCHEMBL7341569 | 0.81 | MEN1 (0.36) | CYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL11138036 | 0.81 | MEN1 (0.39) | CYP1A2CYP2D6MEN1KMT2ADRD4 | |
| SCHEMBL28300124 | 0.81 | MEN1 (0.39) | CYP1A2CYP2D6MEN1KMT2ADRD4 | |
| SCHEMBL7342828 | 0.79 | MEN1 (0.38) | CYP1A2CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358599-A | Synthesis of 4-amino-1,2-hydrocarbyl pyrazolidines via 4-nitro analogs | A. H. ROBINS COMPANY, INC. (US) | 1982-11-09 | — | — | US | claimed |
| EP-0598962-A1 | Imidazole derivatives as calcium channel blockers | NEUROSEARCH A/S (DK) | 1994-06-01 | — | — | EP | disclosed |
| US-5296493-A | Analgesics or antiischemics | NEUROSEARCH A/S (DK) | 1994-03-22 | — | — | US | disclosed |
| US-4358599-A | Synthesis of 4-amino-1,2-hydrocarbyl pyrazolidines via 4-nitro analogs | A. H. ROBINS COMPANY, INC. (US) | 1982-11-09 | — | — | US | disclosed |
| US-4358599-A | Synthesis of 4-amino-1,2-hydrocarbyl pyrazolidines via 4-nitro analogs | A. H. ROBINS COMPANY, INC. (US) | 1982-11-09 | — | — | US | disclosed |
| US-4358599-A | Synthesis of 4-amino-1,2-hydrocarbyl pyrazolidines via 4-nitro analogs | A. H. ROBINS COMPANY, INC. (US) | 1982-11-09 | — | — | US | disclosed |
| US-4309552-A | Synthesis of 4-nitro-1,2-hydrocarbyl pyrazolidines and process for preparation thereof | A. H. ROBINS COMPANY, INC. (US) | 1982-01-05 | — | — | US | disclosed |
| US-4309552-A | Synthesis of 4-nitro-1,2-hydrocarbyl pyrazolidines and process for preparation thereof | A. H. ROBINS COMPANY, INC. (US) | 1982-01-05 | — | — | US | disclosed |