Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.42 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340092 | 1.00 | AHR (0.47) | AHRNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL7293109 | 0.96 | AHR (0.50) | AHRTP53TSHRMAOAMAOB | |
| SCHEMBL9244775 | 0.96 | AHR (0.50) | AHRTP53TSHRMAOAMAOB | |
| SCHEMBL13464287 | 0.85 | NR5A1 (0.54) | AHRNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL7340097 | 0.83 | AHR (0.49) | AHRNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL8619129 | 0.82 | AHR (0.48) | AHRNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL8619126 | 0.82 | AHR (0.48) | AHRNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL6196538 | 0.81 | AHR (0.50) | AHRNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL6196533 | 0.81 | AHR (0.50) | AHRNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL2090761 | 0.81 | AHR (0.53) | AHRTP53TSHRMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4514401-A | CARDIOTONICS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-04-30 | — | — | US | disclosed |
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |