Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340264 | 1.00 | ACE (0.45) | ACEAGTR2KMT2A | |
| SCHEMBL7340398 | 0.86 | ACE (0.48) | ACEAGTR2KMT2A | |
| SCHEMBL7340391 | 0.86 | ACE (0.48) | ACEAGTR2KMT2A | |
| SCHEMBL7350098 | 0.86 | ACE (0.48) | ACEAGTR2KMT2A | |
| SCHEMBL7347386 | 0.84 | ACE (0.47) | ACEAGTR2KMT2A | |
| SCHEMBL7347391 | 0.84 | ACE (0.47) | ACEAGTR2KMT2A | |
| SCHEMBL7346667 | 0.84 | ACE (0.47) | ACE | |
| SCHEMBL7346671 | 0.84 | ACE (0.47) | ACE | |
| SCHEMBL7344158 | 0.83 | ACE (0.50) | ACEKMT2A | |
| SCHEMBL7340813 | 0.83 | ACE (0.50) | ACEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316906-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-02-23 | — | — | US | disclosed |