Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 16/20 | 0.53 |
| ▸ | PDE4A | P27815 | 17/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 13/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 13/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333791 | 1.00 | PDE4D (0.53) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL7333798 | 1.00 | PDE4D (0.53) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL6863990 | 0.89 | PDE4D (0.62) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL7334257 | 0.88 | PDE4D (0.70) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7335619 | 0.88 | PDE4D (0.70) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7334253 | 0.88 | PDE4D (0.70) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL1030283 | 0.85 | PDE4D (0.67) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL7353130 | 0.85 | PDE4D (0.65) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL1028814 | 0.82 | PDE4B (0.71) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL7353023 | 0.82 | PDE4D (0.48) | PDE4DPDE4APDE4BPDE4CABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031476-A1 | AROMATIC HYDROXYETHERS | RHONE-POULENC RORER LIMITED (GB) | 1996-10-10 | — | — | WO | disclosed |