SCHEMBL7340700

SCHEMBL7340700

CCCC1NS(=O)(=O)N(COP(=O)(OCC)OCC)C1=O

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ELANE P08246 7/20 0.42
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7335334 0.73
SCHEMBL7478668 0.66 ELANE (0.65) ELANE
SCHEMBL7330116 0.64 KMT2A (0.35)
Triethyl Phosphate SCHEMBL21887 0.59 TSHR (1.00) TSHR
Triethyl Phosphate SCHEMBL27822049 0.59 TSHR (1.00) TSHR
Triethyl Phosphate SCHEMBL1332591 0.59 TSHR (1.00) TSHR
Triethyl Phosphate SCHEMBL28023664 0.59 TSHR (1.00) TSHR
Triethyl Phosphate SCHEMBL23092283 0.57 TSHR (0.93) TSHR
Triethyl Phosphate SCHEMBL1332661 0.57 TSHR (0.93) TSHR
Triethyl Phosphate SCHEMBL11811931 0.57 TSHR (0.93) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5541168-A PROTEOLYTIC ENZYME INHIBITORS; DEGENERATIVE DISEASES; RESPIRATORY, SKIN, GENETIC AND GASTROINTESTINAL DISORDERS; ANTIARRTHRITIC AND -INFLAMMATORY AGENTS; GENETIC DISEASES STERLING WINTHROP INC. (US) 1996-07-30 US disclosed
WO-1996016970-A1 SUBSTITUTED 2-(PHOSPHINYLOXYMETHYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDES AND COMPOSITIONS AND METHOD OF USE THEREOF SANOFI WINTHROP, INC. (US) 1996-06-06 WO disclosed