Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335247 | 0.89 | AVPR2 (0.70) | AVPR2AVPR1A | |
| SCHEMBL8316848 | 0.85 | AVPR2 (0.74) | AVPR2AVPR1A | |
| SCHEMBL7334828 | 0.85 | AVPR2 (0.65) | AVPR2AVPR1A | |
| SCHEMBL7332025 | 0.84 | AVPR2 (0.64) | AVPR2AVPR1A | |
| SCHEMBL7336426 | 0.84 | AVPR2 (0.70) | AVPR2AVPR1A | |
| SCHEMBL7333306 | 0.83 | AVPR2 (0.64) | AVPR2AVPR1A | |
| SCHEMBL8944611 | 0.82 | AVPR2 (0.68) | AVPR2AVPR1A | |
| SCHEMBL7334191 | 0.82 | AVPR2 (0.68) | AVPR2AVPR1A | |
| SCHEMBL7333018 | 0.82 | AVPR2 (0.70) | AVPR2AVPR1A | |
| SCHEMBL8316071 | 0.79 | AVPR2 (0.63) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968930-A | FOR TREATMENT AND/OR PREVENTION OF HYPERTENSION, CARDIAC INSUFFICIENCY, CORONARY VASOSPASM, CARDIAC ISCHEMIA, RENAL VASOSPASM, LIVER CIRRHOSIS, CONGESTIVE HEART FAILURE, NEPHROTIC SYNDROME, BRAIN EDEMA, CEREBRAL ISCHEMIA | AMERICAN CYANAMID COMPANY (US) | 1999-10-19 | — | — | US | disclosed |
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |
| US-5624923-A | UROGENITAL AND CARDIOVASCULAR DISORDERS | AMERICAN CYANAMID COMPANY (US) | 1997-04-29 | — | — | US | disclosed |