⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2299224 | 0.72 | — | — | |
| SCHEMBL2996874 | 0.72 | — | — | |
| SCHEMBL2299226 | 0.72 | — | — | |
| SCHEMBL6070297 | 0.72 | — | — | |
| SCHEMBL6022443 | 0.69 | — | — | |
| SCHEMBL6022449 | 0.69 | — | — | |
| SCHEMBL5461957 | 0.67 | — | — | |
| SCHEMBL6967474 | 0.67 | — | — | |
| SCHEMBL5442155 | 0.65 | — | — | |
| SCHEMBL200029 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666767-B1 | PHTHALAZINONE DERIVATIVES, METHOD FOR THEIR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION COMPRISING THEM, AND THEIR USE | SHANGHAI INST MATERIA MEDICA CAS (CN) | 2021-12-01 | — | — | EP | claimed |
| US-11040952-B2 | Phthalazinone compound, method for preparation thereof, pharmaceutical composition thereof, and use thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2021-06-22 | — | — | US | claimed |
| CN-109134429-B | Phthalazinone compound, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2021-06-01 | — | — | CN | claimed |
| EP-3666767-A1 | PYRIDAZINONE COMPOUND, METHOD FOR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2020-06-17 | — | — | EP | claimed |
| US-20200181109-A1 | PHTHALAZINONE COMPOUND, METHOD FOR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2020-06-11 | — | — | US | claimed |
| US-10280186-B1 | Silane guanidinate derivatives useful for low temperature deposition of silicon-containing materials | JIANGSU NATA OPTO-ELECTRONIC MATERIAL CO., LTD (CN) | 2019-05-07 | — | — | US | claimed |
| CN-107629740-A | Adhesive, two-sided tape and preparation method thereof | 广州北峻工业材料有限公司 | 2018-01-26 | — | — | CN | claimed |
| CN-105462265-A | High-performance rubber gasket for automobile shock absorber | CHONG XISHAN | 2016-04-06 | — | — | CN | claimed |
| CN-105419005-A | Rubber gasket for an automobile damper with excellent damping performances | CHONG XISHAN | 2016-03-23 | — | — | CN | claimed |
| CN-105199263-A | High performance computer cable sheathing compound | ANHUI LAND GROUP CO LTD | 2015-12-30 | — | — | CN | claimed |
| US-20040147561-A1 | Pyrid-2-one derivatives and methods of use | SYNGENTA CROP PROTECTION AG (CH) | 2004-07-29 | — | — | US | claimed |
| WO-2004060890-A1 | 2-OXOPYRIDIN-3-YL THIA (DI) AZOLE DERIVATES FOR USE IN THE TREATMENT OF CELL PROLIFERATION AND APOPTOSIS RELATED DISEASES | AMGEN INC. (US) | 2004-07-22 | — | — | WO | claimed |
| US-6617324-B1 | Phenyl, cyclohexyl and pyridinyl or pyrimidinyl-substituted | G. D. SEARLE & COMPANY | 2003-09-09 | — | — | US | claimed |
| US-6514977-B1 | For treating p38 kinase mediated disorders | G.D. SEARLE & COMPANY | 2003-02-04 | — | — | US | claimed |
| US-6423713-B1 | Substituted pyrazoles as p38 kinase inhibitors | G. D. SEARLE & COMPANY | 2002-07-23 | — | — | US | claimed |
| EP-1144403-A1 | SUBSTITUED PYRAZOLES AS P38 KINASE INHIBITORS | G.D. SEARLE & CO. (US) | 2001-10-17 | — | — | EP | claimed |
| US-6174638-B1 | EXCELLENT SOLUBILITY IN AN ORGANIC SOLVENT, EXCELLENT COMPATIBILITY WITH A RESIN BINDER AND EXCELLENT PHOTOSENSITIVITY; USEFUL AS AN ELECTRON-TRANSPORTING AGENT FOR THE PHOTOSENSITIVE MATERIAL FOR ELECTROPHOTOGRAPHY | KYOCERA MITA CORPORATION (JP) | 2001-01-16 | — | — | US | claimed |
| WO-2000031063-A1 | SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS | G.D. SEARLE & CO. (US) | 2000-06-02 | — | — | WO | claimed |
| US-4623738-A | ANCHORING FILLER TO POLYMER | KENRICH PETROCHEMICALS, INC. (US) | 1986-11-18 | — | — | US | claimed |
| US-4600789-A | Neoalkoxy organo-titanate useful as coupling and polymer processing agents | KENRICH PETROCHEMICALS, INC. (US) | 1986-07-15 | — | — | US | claimed |