Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 2/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7375753 | 0.92 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BKDM4ERXFP1 | |
| SCHEMBL7336955 | 0.90 | AVPR2 (0.40) | AVPR2AVPR1AAVPR1BKDM4ERXFP1 | |
| SCHEMBL7338327 | 0.88 | AVPR2 (0.43) | AVPR2AVPR1AAVPR1BKDM4EMEN1 | |
| SCHEMBL7339160 | 0.88 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1BKDM4ERXFP1 | |
| SCHEMBL7340008 | 0.84 | CYP19A1 (0.40) | AVPR2AVPR1AAVPR1BSGMS2KDM4E | |
| SCHEMBL7781259 | 0.83 | NPC1 (0.42) | KDM4EMEN1KMT2A | |
| SCHEMBL7336278 | 0.82 | AVPR2 (0.48) | AVPR2AVPR1AAVPR1BKDM4EMEN1 | |
| SCHEMBL7343158 | 0.81 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BRXFP1GAA | |
| SCHEMBL7342173 | 0.81 | AVPR2 (0.43) | AVPR2AVPR1AAVPR1BGAA | |
| Hydrochloric Acid SCHEMBL7780759 | 0.81 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BRXFP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0832061-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |