Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Carbenicillin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.75 |
| ▸ | RECQL | P46063 | 4/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.75 |
| ▸ | HPGD | P15428 | 3/20 | 0.75 |
| ▸ | POLB | P06746 | 2/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | TEK | Q02763 | 1/20 | 0.75 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 4/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | RARB | P10826 | 1/20 | 0.63 |
| ▸ | RARG | P13631 | 1/20 | 0.63 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.63 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.63 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbenicillin SCHEMBL151281 | 1.00 | PTGS1 (0.76) | PTGS1KDM4ERECQLTDP1HPGD | |
| Carbenicillin SCHEMBL11098820 | 1.00 | PTGS1 (0.76) | PTGS1KDM4ERECQLTDP1HPGD | |
| Carbenicillin SCHEMBL11310979 | 0.99 | PTGS1 (0.77) | PTGS1KDM4ERECQLTDP1HPGD | |
| Carbenicillin SCHEMBL11310973 | 0.99 | PTGS1 (0.77) | PTGS1KDM4ERECQLTDP1HPGD | |
| Carbenicillin SCHEMBL3375 | 0.99 | PTGS1 (0.77) | PTGS1KDM4ERECQLTDP1HPGD | |
| Carbenicillin SCHEMBL320405 | 0.99 | PTGS1 (0.77) | PTGS1KDM4ERECQLTDP1HPGD | |
| Carbenicillin SCHEMBL11604897 | 0.99 | PTGS1 (0.77) | PTGS1KDM4ERECQLTDP1HPGD | |
| Carbenicillin SCHEMBL8402462 | 0.99 | PTGS1 (0.77) | PTGS1KDM4ERECQLTDP1HPGD | |
| Carbenicillin SCHEMBL10520792 | 0.99 | PTGS1 (0.77) | PTGS1KDM4ERECQLTDP1HPGD | |
| Carbenicillin SCHEMBL13662704 | 0.99 | PTGS1 (0.77) | PTGS1KDM4ERECQLTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117982740-B | Absorbable biomedical polymer material, ligature clip and preparation method | 四川国纳科技有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-117982740-A | Absorbable biomedical polymer material, ligature clip and preparation method | 四川国纳科技有限公司 | 2024-05-07 | — | — | CN | claimed |
| WO-2021156838-A1 | TIO2 NANO-PARTICLES IMPREGNATED SURGICAL SILK SUTURE | CHANDRASHEKAR VIDYA KODIGE (IN) | 2021-08-12 | — | — | WO | claimed |
| US-4024871-A | POLYURETHANE | ETHICON, INC. (US) | 1977-05-24 | — | — | US | claimed |
| US-3987797-A | ANTIMICROBIAL SUTURES | ETHICON, INC. (US) | 1976-10-26 | — | — | US | claimed |
| CN-119372180-B | Cas protein, composition and application thereof | 上海尧唐生物科技股份有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-119372181-B | Nuclease protein and application thereof | 上海尧唐生物科技股份有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-119979597-A | Application of rice OsKNOX gene in regulation and control of salt tolerance | 南京农业大学 | 2025-05-13 | — | — | CN | disclosed |
| CN-119790157-A | Double-stranded circular DNA vector, method for producing linear covalently closed DNA, and fusion polypeptide comprising a telomerase and an endonuclease | 株式会社钟化 | 2025-04-08 | — | — | CN | disclosed |
| CN-113861268-B | Cell penetrating peptides and methods of making and using the same | 恩特拉达治疗学股份有限公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-118745431-B | Rice salt tolerance related gene OsBLH4, encoding protein and application thereof | 南京农业大学 | 2025-02-14 | — | — | CN | disclosed |
| CN-119410607-A | Cas effect protein, composition and application | 尧唐(南京)生物科技有限公司 | 2025-02-11 | — | — | CN | disclosed |
| EP-0069232-B1 | PHARMACEUTICAL COMPOSITION COMPRISING PHENYL ACETYL GLUTAMINE,A COMBINATION OF THIS COMPOUND WITH PHENYLACETIC ACID OR 3-(PHENYLACETYLAMINO)PIPERIDINE-2,6-DIONE,A PROCESS FOR ISOLATING THE LATTER FROM URINE AND A PROCESS FOR THE SYNTHESIS OF 3-(PHENYLACETYLAMINO)PIPERIDINE-2,6-DIONE | BURZYNSKI, Stanislaw R. (US) | 1986-10-29 | — | — | EP | disclosed |
| US-4559325-A | ANTITUMOR AGENTS | BURZYNSKI STANISLAW R (US) | 1985-12-17 | — | — | US | disclosed |
| US-4558057-A | URINE EXTRACTS | BURZYNSKI STANISLAW R (US) | 1985-12-10 | — | — | US | disclosed |
| US-4470970-A | ANTITUMOR AND-CARCINOGENIC AGENT EXTRACTED FROM URINE | BURZYNSKI STANISLAW R | 1984-09-11 | — | — | US | disclosed |
| EP-0069232-A2 | Pharmaceutical composition comprising phenyl acetyl glutamine,a combination of this compound with phenylacetic acid or 3-(phenylacetylamino)piperidine-2,6-dione,a process for isolating the latter from urine and a process for the synthesis of 3-(phenylacetylamino)piperidine-2,6-dione | BURZYNSKI, Stanislaw R. (US) | 1983-01-12 | — | — | EP | disclosed |
| US-4024871-A | POLYURETHANE | ETHICON, INC. (US) | 1977-05-24 | — | — | US | disclosed |
| US-4014745-A | LUMINESCENCE | NASA | 1977-03-29 | — | — | US | disclosed |
| US-3987797-A | ANTIMICROBIAL SUTURES | ETHICON, INC. (US) | 1976-10-26 | — | — | US | disclosed |