Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 14/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 3/20 | 0.54 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343904 | 0.81 | BCHE (1.00) | BCHEPOLBATMCYP2D6TSHR | |
| SCHEMBL4780247 | 0.74 | BCHE (0.61) | BCHEACHENOX1HTR1AHTR2A | |
| SCHEMBL8426443 | 0.72 | BCHE (0.63) | BCHEPOLBATMCYP2D6TSHR | |
| SCHEMBL8428712 | 0.72 | BCHE (1.00) | BCHEPOLBATMCYP2D6TSHR | |
| SCHEMBL7350072 | 0.72 | BCHE (0.63) | BCHEPOLBATMCYP2D6TSHR | |
| SCHEMBL28790339 | 0.72 | BCHE (0.41) | BCHEPOLBATMCYP2D6TSHR | |
| SCHEMBL17670562 | 0.71 | NOX1 (0.55) | BCHEPOLBATMACHENOX1 | |
| SCHEMBL627575 | 0.71 | BCHE (0.65) | BCHEPOLBATMACHENOX1 | |
| Dacemazine SCHEMBL141968 | 0.71 | BCHE (0.63) | BCHEPOLBATMACHENOX1 | |
| Dacemazine SCHEMBL29546195 | 0.71 | BCHE (0.63) | BCHEPOLBATMACHENOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4833138-A | Phenothiazinealkaneamines for treatment of neurotoxic injury | WASHINGTON UNIVERSITY (US) | 1989-05-23 | — | — | US | disclosed |