Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.79 |
| ▸ | RAB9A | P51151 | 5/20 | 0.79 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.79 |
| ▸ | HTT | P42858 | 2/20 | 0.79 |
| ▸ | GLA | P06280 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.79 |
| ▸ | RNF4 | P78317 | 1/20 | 0.67 |
| ▸ | JAK2 | O60674 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5452605 | 0.89 | NPC1 (1.00) | NPC1RAB9APAX8ALDH1A1HTT | |
| SCHEMBL22823801 | 0.82 | RNF4 (0.79) | NPC1RAB9APAX8ALDH1A1HTT | |
| SCHEMBL23518793 | 0.82 | RNF4 (0.85) | NPC1RAB9APAX8ALDH1A1HTT | |
| SCHEMBL22526191 | 0.80 | RNF4 (0.81) | NPC1RAB9APAX8ALDH1A1HTT | |
| SCHEMBL22823726 | 0.80 | RNF4 (1.00) | NPC1RAB9APAX8ALDH1A1HTT | |
| SCHEMBL22525721 | 0.79 | RNF4 (0.79) | NPC1RAB9APAX8ALDH1A1HTT | |
| SCHEMBL10426810 | 0.79 | NPC1 (0.65) | NPC1RAB9APAX8ALDH1A1HTT | |
| SCHEMBL21105957 | 0.79 | RNF4 (0.79) | NPC1RAB9APAX8ALDH1A1HTT | |
| SCHEMBL23518716 | 0.78 | RNF4 (0.77) | NPC1RAB9APAX8ALDH1A1HTT | |
| SCHEMBL20463428 | 0.78 | NPC1 (0.68) | NPC1RAB9APAX8ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585500-A1 | Diaryl piperazineacetamides as antimuscarinic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-09 | — | — | EP | disclosed |