⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258196 | 1.00 | — | — | |
| SCHEMBL3423923 | 1.00 | TRIM24 (0.38) | — | |
| SCHEMBL21114263 | 1.00 | TRIM24 (0.38) | — | |
| SCHEMBL8432414 | 1.00 | TRIM24 (0.38) | — | |
| SCHEMBL5400 | 1.00 | — | — | |
| SCHEMBL8081626 | 1.00 | TRIM24 (0.38) | — | |
| SCHEMBL7732749 | 1.00 | TRIM24 (0.38) | — | |
| Water SCHEMBL22163893 | 0.96 | — | — | |
| SCHEMBL5359 | 0.95 | — | — | |
| SCHEMBL5682760 | 0.91 | TRIM24 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024126648-A1 | SULFOXIMINES AS INHIBITORS OF NaV1.8 | Grünenthal GmbH (DE) | 2024-06-20 | — | — | WO | claimed |
| EP-4385984-A1 | PYRIDINE-N-OXIDES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2024-06-19 | — | — | EP | claimed |
| CN-116199747-A | Lidamycin prodrug, preparation method and application thereof in preparation of antitumor drugs | 中国医学科学院医药生物技术研究所 | 2023-06-02 | — | — | CN | claimed |
| WO-2020239050-A1 | 2-(2-CHLORO-4-METHYLPHENYL)QUINAZOLINE-4(3H)-KETONE COMPOUND AND MEDICAL USE THEREOF | 中国人民解放军军事科学院军事医学研究院 | 2020-12-03 | — | — | WO | claimed |
| CN-107001532-B | Copolymer and aqueous coating composition using same | 株式会社ADEKA | 2020-11-20 | — | — | CN | claimed |
| CN-110041273-B | 2- (2-chloro-4-methylphenyl) quinazoline-4 (3H) -ketone compound and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-10-20 | — | — | CN | claimed |
| EP-3045485-B1 | POLYISOCYANATE MODIFIED WITH SULPHAMIC ACID, PREPARATION METHOD THEREFOR AND USE THEREOF | WANHUA CHEMICAL GROUP CO LTD (CN) | 2020-03-25 | — | — | EP | claimed |
| CN-110041273-A | 2- (the chloro- 4- aminomethyl phenyl of 2-) quinazoline -4 (3H) -one class compound and its medical usage | 中国人民解放军军事科学院军事医学研究院 | 2019-07-23 | — | — | CN | claimed |
| CN-109265995-A | A kind of polymerized hindered amine light stabilizer and its application | 北京天罡助剂有限责任公司 | 2019-01-25 | — | — | CN | claimed |
| US-9975985-B2 | Polyisocyanate modified with sulphamic acid, preparation method thereof and use thereof | WANHUA CHEMICAL GROUP CO., LTD. (CN) | 2018-05-22 | — | — | US | claimed |
| US-20160280836-A1 | POLYISOCYANATE MODIFIED WITH SULPHAMIC ACID, PREPARATION METHOD THEREOF AND USE THEREOF | WANHUA CHEMICAL GROUP CO., LTD. (CN) | 2016-09-29 | — | — | US | claimed |
| EP-3045485-A1 | POLYISOCYANATE MODIFIED WITH SULPHAMIC ACID, PREPARATION METHOD THEREFOR AND USE THEREOF | Wanhua Chemical Group Co., Ltd. (CN) | 2016-07-20 | — | — | EP | claimed |
| EP-1865949-A2 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Incorporated (US) | 2007-12-19 | — | — | EP | claimed |
| WO-2006099256-A2 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2006-09-21 | — | — | WO | claimed |
| CN-118290394-A | Preparation of light-controlled targeting GSPT protein degradation compound and application thereof in tumor treatment | 中国医学科学院药物研究所 | 2024-07-05 | — | — | CN | disclosed |
| CN-118284670-A | Colored resin composition, colored resin composition set, and color filter | 三菱化学株式会社 | 2024-07-02 | — | — | CN | disclosed |
| WO-2024126648-A1 | SULFOXIMINES AS INHIBITORS OF NaV1.8 | Grünenthal GmbH (DE) | 2024-06-20 | — | — | WO | disclosed |
| US-4278129-A | Stimulation of oil and gas wells with phosphate ester surfactants | BASF WYANDOTTE CORPORATION (US) | 1981-07-14 | — | — | US | disclosed |
| US-4194008-A | INSECTICIDE, FUNGICIDE, MITICIDE, PARASITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-18 | — | — | US | disclosed |
| US-4033993-A | Cycloalkyl carbonates | HENKEL & CIE G.M.B.H. (DT) | 1977-07-05 | — | — | US | disclosed |