SCHEMBL7343147

SCHEMBL7343147

CC(C)C(=O)Nc1ccc(C(=O)Oc2cc(Cl)cc(OS(=O)(=O)C=Cc3ccccc3)c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARG P37231 11/20 0.52
ALDH1A1 P00352 2/20 0.41
HTT P42858 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 1/20 0.41
RAB9A P51151 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
NFE2L2 Q16236 5/20 0.41
LMNA P02545 2/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7343139 1.00 PPARG (0.52) PPARGALDH1A1HTTSMN1; SMN2HPGD
SCHEMBL9689310 0.86 PPARG (0.50) PPARGSMN1; SMN2NFE2L2LMNAMEN1
SCHEMBL9689305 0.86 PPARG (0.50) PPARGSMN1; SMN2NFE2L2LMNAMEN1
SCHEMBL7330717 0.85 KMT2A (0.46) ALDH1A1HTTSMN1; SMN2HPGDRAB9A
SCHEMBL7330713 0.85 KMT2A (0.46) ALDH1A1HTTSMN1; SMN2HPGDRAB9A
SCHEMBL9690405 0.85 PPARG (0.50) PPARGSMN1; SMN2NFE2L2LMNAMEN1
SCHEMBL7338290 0.84 KMT2A (0.46) ALDH1A1HTTSMN1; SMN2HPGDRAB9A
SCHEMBL7333607 0.84 ENPP1 (0.53) ALDH1A1HTTSMN1; SMN2HPGDRAB9A
SCHEMBL7335767 0.81 KMT2A (0.44) ALDH1A1HTTSMN1; SMN2HPGDRAB9A
SCHEMBL7343143 0.81 PPARG (0.46) PPARGALDH1A1HTTSMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0475531-B1 Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same ASAHI CHEMICAL IND (JP) 1995-01-18 EP disclosed
EP-0475531-A1 Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1992-03-18 EP disclosed