Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4140962 | 1.00 | SLC6A2 (0.53) | SLC6A2PDE4DTSHRKDM4EPOLB | |
| SCHEMBL31081717 | 1.00 | SLC6A2 (0.53) | SLC6A2PDE4DTSHRKDM4EPOLB | |
| SCHEMBL7349197 | 1.00 | SLC6A2 (0.53) | SLC6A2PDE4DTSHRKDM4EPOLB | |
| SCHEMBL15498506 | 1.00 | SLC6A2 (0.53) | SLC6A2PDE4DTSHRKDM4EPOLB | |
| SCHEMBL4140966 | 1.00 | SLC6A2 (0.53) | SLC6A2PDE4DTSHRKDM4EPOLB | |
| SCHEMBL4140963 | 1.00 | SLC6A2 (0.53) | SLC6A2PDE4DTSHRKDM4EPOLB | |
| SCHEMBL8662256 | 1.00 | SLC6A2 (0.53) | SLC6A2PDE4DTSHRKDM4EPOLB | |
| SCHEMBL24215035 | 0.90 | TSHR (0.61) | SLC6A2PDE4DTSHRTAAR1LMNA | |
| SCHEMBL9679098 | 0.90 | TSHR (0.61) | SLC6A2PDE4DTSHRTAAR1LMNA | |
| SCHEMBL13941992 | 0.90 | TSHR (0.61) | SLC6A2PDE4DTSHRTAAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153589-A | FOR TREATING VIRAL INFECTIONS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2000-11-28 | — | — | US | disclosed |
| US-5190969-A | Epoxy derivatives of amino acids as viricides for treatment of HIV infections | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 1993-03-02 | — | — | US | disclosed |