Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 8/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343687 | 0.93 | TACR2 (0.53) | TACR2ITGB3ITGA2BHRH3NPC1 | |
| SCHEMBL7337619 | 0.91 | CACNA1B (0.57) | TACR2CACNA1B | |
| SCHEMBL7340969 | 0.91 | CACNA1B (0.57) | TACR2CACNA1B | |
| SCHEMBL7336892 | 0.90 | TACR2 (0.54) | TACR2ITGB3ITGA2BHRH3NPC1 | |
| SCHEMBL7346404 | 0.89 | TACR2 (0.50) | TACR2ITGB3ITGA2BNPC1RAB9A | |
| SCHEMBL7349125 | 0.89 | TACR2 (0.50) | TACR2ITGB3ITGA2BCACNA1B | |
| SCHEMBL7340850 | 0.88 | TACR2 (0.49) | TACR2ITGB3ITGA2BCACNA1BEGFR | |
| SCHEMBL7341412 | 0.86 | TACR2 (0.58) | TACR2ITGB3ITGA2BCACNA1B | |
| SCHEMBL7345251 | 0.86 | TACR2 (0.60) | TACR2CACNA1B | |
| SCHEMBL7342593 | 0.86 | TACR2 (0.58) | TACR2CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |