Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 8/20 | 0.69 |
| ▸ | PLAU | P00749 | 9/20 | 0.60 |
| ▸ | PLG | P00747 | 4/20 | 0.54 |
| ▸ | PLAT | P00750 | 4/20 | 0.54 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.54 |
| ▸ | F2 | P00734 | 3/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | KLK1 | P06870 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7341167 | 0.95 | TMPRSS2 (0.63) | TMPRSS2PLAUPLGPLATKLKB1 | |
| SCHEMBL7344372 | 0.86 | TMPRSS2 (0.56) | TMPRSS2PLAUTMEM97SIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL7341178 | 0.82 | TMPRSS2 (0.52) | TMPRSS2PLAUTMEM97SIGMAR1 | |
| SCHEMBL6292442 | 0.81 | TMEM97 (0.62) | TMPRSS2TMEM97SIGMAR1 | |
| SCHEMBL7341174 | 0.79 | PLAU (0.47) | TMPRSS2PLAUPLGPLATKLKB1 | |
| SCHEMBL1082437 | 0.78 | TMEM97 (0.64) | TMEM97SIGMAR1 | |
| SCHEMBL23651925 | 0.77 | TMPRSS2 (0.49) | TMPRSS2TMEM97SIGMAR1 | |
| SCHEMBL6296029 | 0.77 | TMEM97 (0.62) | TMPRSS2TMEM97SIGMAR1 | |
| SCHEMBL31173403 | 0.77 | TMEM97 (0.68) | TMEM97SIGMAR1 | |
| SCHEMBL1027550 | 0.77 | TMEM97 (0.67) | TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |