Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL11117548 | 1.00 | EBP (0.40) | EBPSIGMAR1KDM4EMEN1KMT2A | |
| Oxalic Acid SCHEMBL11123674 | 1.00 | EBP (0.40) | EBPSIGMAR1KDM4EMEN1KMT2A | |
| Oxalic Acid SCHEMBL7355984 | 1.00 | EBP (0.40) | EBPSIGMAR1KDM4EMEN1KMT2A | |
| Oxalic Acid SCHEMBL7356529 | 0.97 | EBP (0.44) | EBPSIGMAR1KDM4EMEN1KMT2A | |
| Oxalic Acid SCHEMBL7348916 | 0.97 | EBP (0.44) | EBPSIGMAR1KDM4EMEN1KMT2A | |
| Oxalic Acid SCHEMBL11122865 | 0.97 | EBP (0.44) | EBPSIGMAR1KDM4EMEN1KMT2A | |
| Oxalic Acid SCHEMBL11120414 | 0.97 | EBP (0.44) | EBPSIGMAR1KDM4EMEN1KMT2A | |
| SCHEMBL7349400 | 0.96 | EBP (0.41) | EBPSIGMAR1PPARAPPARGEPHX2 | |
| SCHEMBL7349405 | 0.96 | EBP (0.41) | EBPSIGMAR1PPARAPPARGEPHX2 | |
| SCHEMBL7348593 | 0.96 | EBP (0.41) | EBPSIGMAR1PPARAPPARGEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438131-A | CARDIOVASCULAR DISORDERS | BASF AKTIENGESELLSCHAFT (DE) | 1984-03-20 | — | — | US | disclosed |
| EP-0064158-A1 | Omega-cyano-1, omega-diphenyl azalcane derivatives, their preparation and pharmaceutical preparations containing them | BASF Aktiengesellschaft (DE) | 1982-11-10 | — | — | EP | disclosed |