Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 1/20 | 0.47 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345020 | 0.87 | AVPR2 (0.48) | AVPR2AVPR1A | |
| SCHEMBL7344348 | 0.87 | AVPR2 (0.48) | AVPR2AVPR1A | |
| SCHEMBL7349122 | 0.86 | NPC1 (0.43) | — | |
| SCHEMBL7350266 | 0.85 | AVPR2 (0.47) | AVPR2AVPR1A | |
| SCHEMBL7348040 | 0.84 | AVPR2 (0.46) | AVPR2AVPR1A | |
| SCHEMBL7352060 | 0.83 | AVPR1A (0.47) | AVPR2AVPR1A | |
| SCHEMBL7344199 | 0.79 | — | — | |
| SCHEMBL8559349 | 0.79 | AVPR2 (0.60) | AVPR2AVPR1A | |
| SCHEMBL7350463 | 0.79 | — | — | |
| SCHEMBL8712808 | 0.79 | AVPR2 (0.49) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985869-A | USEFUL AS VASODILATORS, HYPOTENSIVE AGENTS, WATER DIURETICS, PLATELET AGGLUTINATION INHIBITORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1999-11-16 | — | — | US | disclosed |
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5559230-A | VASOPRESSIN ANTAGONISTS, QUINOLINES, BENZAZEPINES, VASODILATION, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0450097-B1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| EP-0450097-A1 | BENZOHETEROCYCLIC COMPOUNDS. | OTSUKA PHARMA CO LTD (JP) | 1991-10-09 | — | — | EP | disclosed |
| WO-1991005549-A1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | WO | disclosed |