Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 18/20 | 0.59 |
| ▸ | GRIN2D | O15399 | 15/20 | 0.59 |
| ▸ | GRIN3B | O60391 | 15/20 | 0.59 |
| ▸ | GRIN2A | Q12879 | 15/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 15/20 | 0.59 |
| ▸ | GRIN2C | Q14957 | 15/20 | 0.59 |
| ▸ | GRIN3A | Q8TCU5 | 15/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351656 | 0.83 | GRIN1 (0.62) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL7786483 | 0.75 | GRIN1 (1.00) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL7786503 | 0.74 | GRIN2D (0.46) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL7810378 | 0.74 | GRIN1 (0.69) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL1291840 | 0.72 | GRIN2D (0.61) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL7784700 | 0.70 | GRIN2D (0.53) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL7467072 | 0.70 | GRIN2D (1.00) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL7786927 | 0.70 | GRIN2D (0.59) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8904175 | 0.67 | GRIN2D (1.00) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL2593981 | 0.67 | KDM4E (0.60) | KDM4EHSD17B10ALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005337-A1 | USE OF GABA AND NMDA RECEPTOR LIGANDS FOR THE TREATMENT OF MIGRAINE HEADACHE | COCENSYS, INC. (US) | 1998-02-12 | — | — | WO | disclosed |