Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.72 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.72 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28674746 | 0.91 | ESR1 (0.85) | ESR1ESR2PDCD1CD274NCOA3 | |
| SCHEMBL20483494 | 0.87 | ESR1 (0.79) | ESR1ESR2PDCD1CD274NCOA3 | |
| SCHEMBL7475625 | 0.85 | ESR1 (0.77) | ESR1ESR2PDCD1CD274NCOA3 | |
| SCHEMBL930710 | 0.84 | ESR1 (1.00) | ESR1ESR2PDCD1CD274NCOA3 | |
| SCHEMBL27304353 | 0.82 | ESR1 (0.72) | ESR1ESR2PDCD1CD274NCOA3 | |
| SCHEMBL13545800 | 0.82 | ESR1 (0.72) | ESR1ESR2PDCD1CD274NCOA3 | |
| SCHEMBL13545931 | 0.82 | ESR1 (0.72) | ESR1ESR2PDCD1CD274NCOA3 | |
| Phosphonic Acid SCHEMBL28025735 | 0.80 | ESR1 (0.69) | ESR1ESR2PDCD1CD274NCOA3 | |
| SCHEMBL11259468 | 0.79 | ESR1 (0.68) | ESR1ESR2PDCD1CD274NCOA3 | |
| SCHEMBL9800092 | 0.79 | ESR1 (0.68) | ESR1ESR2PDCD1CD274NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505413-B1 | BETA-LACTAM DERIVATIVES | ERBA CARLO SPA (IT) | 1994-08-31 | — | — | EP | claimed |
| WO-1991009036-A1 | BETA-LACTAM DERIVATIVES | FARMITALIA CARLO ERBA S.R.L. (IT) | 1991-06-27 | — | — | WO | claimed |
| US-5348952-A | Antibiotics for antiinflammatory agents, degenerative diseases caused by proteolytic enzymes and respiratory system disorders | FARMITALIA CARLO ERBA S.R.L. (IT) | 1994-09-20 | — | — | US | disclosed |
| EP-0505413-B1 | BETA-LACTAM DERIVATIVES | ERBA CARLO SPA (IT) | 1994-08-31 | — | — | EP | disclosed |