Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.55 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | MMP9 | P14780 | 3/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345887 | 0.91 | F2 (0.62) | F2MMP2MMP9 | |
| SCHEMBL6971414 | 0.87 | F2 (0.57) | F2 | |
| SCHEMBL7350482 | 0.87 | F2 (0.57) | F2 | |
| SCHEMBL7335493 | 0.86 | F2 (0.64) | F2 | |
| SCHEMBL7342636 | 0.86 | F2 (0.64) | F2 | |
| SCHEMBL7341634 | 0.83 | F2 (0.59) | F2 | |
| SCHEMBL7340279 | 0.83 | F2 (0.59) | F2 | |
| SCHEMBL7342278 | 0.81 | F2 (0.67) | F2 | |
| SCHEMBL7342103 | 0.81 | F2 (0.67) | F2 | |
| SCHEMBL7309132 | 0.78 | F2 (0.58) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601459-A2 | Sulfonamido heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-15 | — | — | EP | claimed |