Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | IDO1 | P14902 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | CNR2 | P34972 | 13/20 | 0.63 |
| ▸ | CNR1 | P21554 | 8/20 | 0.63 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29051451 | 0.87 | KDM4E (0.74) | KDM4EIDO1HTTCNR2S1PR1 | |
| SCHEMBL5444289 | 0.84 | CHRM1 (0.51) | KDM4EIDO1HTTCNR2CNR1 | |
| SCHEMBL2039750 | 0.83 | KDM4E (0.61) | KDM4EIDO1HTTCNR2CNR1 | |
| SCHEMBL7347589 | 0.83 | CNR2 (0.69) | KDM4ECNR2CNR1 | |
| SCHEMBL2643685 | 0.82 | IDO1 (0.48) | KDM4EIDO1HTTCNR2CNR1 | |
| SCHEMBL2186845 | 0.81 | KDM4E (0.74) | KDM4EIDO1HTTCNR2CNR1 | |
| SCHEMBL3350909 | 0.81 | KDM4E (0.46) | KDM4EIDO1HTTCNR2CNR1 | |
| SCHEMBL14411123 | 0.81 | KDM4E (0.49) | KDM4EIDO1HTTCNR2CNR1 | |
| SCHEMBL176994 | 0.80 | S1PR1 (0.75) | KDM4EIDO1HTTCNR2CNR1 | |
| SCHEMBL2187242 | 0.80 | KDM4E (0.72) | KDM4EIDO1HTTS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760815-A1 | PROCESSES FOR PREPARING 1-BUTYL-2-[2'-(2H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-1H-INDOLE-3-CARBOXYLIC ACID | SYNTEX (U.S.A.) INC. (US) | 1997-03-12 | — | — | EP | disclosed |
| US-5527918-A | Processes for preparing 1-butyl-2-[2'-(2H-tetrazol-5-yl) biphenyl-4-ylmethyl]-1H-indole-3-carboxylic acid | SYNTEX (U.S.A.) INC. (US) | 1996-06-18 | — | — | US | disclosed |
| WO-1995032962-A1 | PROCESSES FOR PREPARING 1-BUTYL-2-[2'-(2H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-1H-INDOLE-3-CARBOXYLIC ACID | SYNTEX (U.S.A.) INC. (US) | 1995-12-07 | — | — | WO | disclosed |
| US-5446121-A | Processes for preparing 1-butyl-2-[2'-(2H-tetrazol-5-yl) biphenyl-4-ylmethyl]-1H-indole-3-carboxylic acid | SYNTEX (U.S.A.) INC. (US) | 1995-08-29 | — | — | US | disclosed |
| US-5412102-A | Processes for preparing 1-butyl-2-[2'-(2H-tetrazol-5-yl) biphenyl-4-ylmethyl]-1H-indole-3-carboxylic acid | SYNTEX (U.S.A.) INC. (US) | 1995-05-02 | — | — | US | disclosed |