Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 10/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.48 |
| ▸ | IL1RN | P18510 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | YAP1 | P46937 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347682 | 0.92 | CACNA1B (0.51) | CACNA1BOPRK1IL1RNERAP2ERAP1 | |
| SCHEMBL7338900 | 0.90 | CACNA1B (0.50) | CACNA1BOPRK1IL1RNERAP2ERAP1 | |
| SCHEMBL7343479 | 0.90 | CACNA1B (0.55) | CACNA1BOPRK1IL1RNERAP2ERAP1 | |
| SCHEMBL7340762 | 0.89 | CACNA1B (0.59) | CACNA1BOPRK1IL1RNERAP2ERAP1 | |
| SCHEMBL7340061 | 0.87 | CACNA1B (0.52) | CACNA1BOPRK1IL1RNERAP2ERAP1 | |
| SCHEMBL7347989 | 0.86 | CACNA1B (0.53) | CACNA1BOPRK1YAP1 | |
| SCHEMBL7339911 | 0.85 | CACNA1B (0.52) | CACNA1BOPRK1IL1RNERAP2ERAP1 | |
| SCHEMBL7336001 | 0.85 | CACNA1B (0.52) | CACNA1BOPRK1IL1RNERAP2ERAP1 | |
| SCHEMBL7348697 | 0.85 | CACNA1B (0.51) | CACNA1BOPRK1IL1RNERAP2ERAP1 | |
| SCHEMBL7345176 | 0.85 | CACNA1B (0.57) | CACNA1BOPRK1DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |