Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.85 |
| ▸ | HPGD | P15428 | 5/20 | 0.85 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.85 |
| ▸ | MEN1 | O00255 | 2/20 | 0.85 |
| ▸ | GAA | P10253 | 2/20 | 0.85 |
| ▸ | MAPT | P10636 | 2/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.85 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.85 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.85 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.85 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.81 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | ITGB3 | P05106 | 13/20 | 0.67 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.67 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.61 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.61 |
| ▸ | ITGAL | P20701 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1198997 | 0.92 | KDM4E (0.71) | KDM4EHPGDL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL1198891 | 0.91 | KDM4E (0.85) | KDM4EHPGDL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL1198615 | 0.90 | KDM4E (0.83) | KDM4EHPGDL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL1198047 | 0.89 | KDM4E (0.82) | KDM4EHPGDL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL1198295 | 0.89 | KDM4E (0.82) | KDM4EHPGDL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL1198576 | 0.86 | KDM4E (0.83) | KDM4EALDH1A1MEN1KMT2AITGB3 | |
| SCHEMBL1198425 | 0.85 | KDM4E (0.78) | KDM4EHPGDL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL1197613 | 0.85 | KDM4E (0.77) | KDM4EHPGDL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL1198717 | 0.84 | KDM4E (0.73) | KDM4EHPGDL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL1198481 | 0.84 | KDM4E (0.63) | KDM4EHPGDL3MBTL1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342851-A | Useful in methods of treating reperfusion thrombosis injury | MCNEIL-PPC, INC. (US) | 1994-08-30 | — | — | US | disclosed |