SCHEMBL7347161

SCHEMBL7347161

CC([C]=O)c1c[nH]cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8183850 0.76
SCHEMBL2006067 0.76
SCHEMBL16508915 0.71
SCHEMBL2673476 0.71
SCHEMBL2367442 0.71
SCHEMBL24874217 0.71
SCHEMBL15478600 0.71
SCHEMBL23153772 0.71
SCHEMBL5512862 0.71
SCHEMBL7347165 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109310756-B Novel angiopoietin 2, VEGF bispecific antagonists 奥美药业有限公司 2022-06-28 CN disclosed
CN-109414500-B PD-L1 specific monoclonal antibody for treatment and diagnosis 奥美药业有限公司 2022-02-25 CN disclosed
EP-2347762-B1 EXENDIN FOR TREATING DIABETES AND REDUCING BODY WEIGHT AMYLIN PHARMACEUTICALS LLC (US) 2019-05-08 EP disclosed
EP-2303313-B1 EXENDINS TO LOWER CHOLESTROL AND TRIGLYCERIDES AMYLIN PHARMACEUTICALS LLC (US) 2015-10-28 EP disclosed
EP-1971362-B1 EXENDIN FOR TREATING DIABETES AND REDUCING BODY WEIGHT AMYLIN PHARMACEUTICALS LLC (US) 2014-12-03 EP disclosed
US-5985869-A USEFUL AS VASODILATORS, HYPOTENSIVE AGENTS, WATER DIURETICS, PLATELET AGGLUTINATION INHIBITORS OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1999-11-16 US disclosed
US-5753677-A Benzoheterocyclic compounds OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1998-05-19 US disclosed
US-5559230-A VASOPRESSIN ANTAGONISTS, QUINOLINES, BENZAZEPINES, VASODILATION, HYPOTENSIVE AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1996-09-24 US disclosed
US-5521179-A Heterocyclic amides ZENECA LIMITED (GB) 1996-05-28 US disclosed
EP-0450097-B1 BENZOHETEROCYCLIC COMPOUNDS OTSUKA PHARMA CO LTD (JP) 1996-04-24 EP disclosed
EP-0663834-A4 GROWTH HORMONE RELEASING PEPTIDES. SMITHKLINE BEECHAM CORP (US) 1996-01-24 EP disclosed
EP-0663834-A1 GROWTH HORMONE RELEASING PEPTIDES SMITHKLINE BEECHAM CORPORATION (US) 1995-07-26 EP disclosed
EP-0602209-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-06-22 EP disclosed
WO-1994007519-A1 GROWTH HORMONE RELEASING PEPTIDES SMITHKLINE BEECHAM CORPORATION (US) 1994-04-14 WO disclosed
WO-1994001113-A1 OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1994-01-20 WO disclosed
EP-0450097-A1 BENZOHETEROCYCLIC COMPOUNDS. OTSUKA PHARMA CO LTD (JP) 1991-10-09 EP disclosed
WO-1991005549-A1 BENZOHETEROCYCLIC COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-05-02 WO disclosed
EP-0074229-A1 Triazole gastric anti-secretory agents PFIZER INC. (US) 1983-03-16 EP disclosed