⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347230 | 1.00 | — | — | |
| SCHEMBL2272281 | 1.00 | — | — | |
| SCHEMBL2268627 | 1.00 | — | — | |
| SCHEMBL7348502 | 0.94 | — | — | |
| SCHEMBL7348503 | 0.94 | — | — | |
| SCHEMBL6157905 | 0.94 | — | — | |
| SCHEMBL7782125 | 0.78 | — | — | |
| SCHEMBL7866676 | 0.72 | — | — | |
| SCHEMBL12133538 | 0.72 | — | — | |
| SCHEMBL1350955 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015179743-A1 | LIBRARY AND SCREENING APPROACH FOR IMPROVED CELL PENETRATING PEPTIDES | GENZYME CORPORATION (US) | 2015-11-26 | — | — | WO | claimed |
| US-5538997-A | HIV PROTEINASE INHIBITORS | SANDOZ LTD. (CH) | 1996-07-23 | — | — | US | claimed |
| EP-0615969-A1 | 2,4-Diamino-3-hydroxycarboxylic acid derivatives | SANDOZ LTD. (CH) | 1994-09-21 | — | — | EP | claimed |
| US-11801311-B2 | Inhibiting or downregulating glycogen synthase by creating premature stop codons using antisense oligonucleotides | GENZYME CORPORATION (US) | 2023-10-31 | — | — | US | disclosed |
| EP-3795687-A1 | INHIBITING OR DOWNREGULATING GLYCOGEN SYNTHASE BY CREATING PREMATURE STOP CODONS USING ANTISENSE OLIGONUCLEOTIDES | Genzyme Corporation (US) | 2021-03-24 | — | — | EP | disclosed |
| US-20210030893-A1 | INHIBITING OR DOWNREGULATING GLYCOGEN SYNTHASE BY CREATING PREMATURE STOP CODONS USING ANTISENSE OLIGONUCLEOTIDES | GENZYME CORPORATION | 2021-02-04 | — | — | US | disclosed |
| EP-3146050-B1 | INHIBITING OR DOWNREGULATING GLYCOGEN SYNTHASE BY CREATING PREMATURE STOP CODONS USING ANTISENSE OLIGONUCLEOTIDES | GENZYME CORP (US) | 2020-08-12 | — | — | EP | disclosed |
| US-10682423-B2 | Inhibiting or downregulating glycogen synthase by creating premature stop codons using antisense oligonucleotides | GENZYME CORPORATION (US) | 2020-06-16 | — | — | US | disclosed |
| CN-106459975-B | Multiple oligonucleotide moieties on peptide carriers | 建新公司 | 2020-03-27 | — | — | CN | disclosed |
| US-20190117794-A1 | INHIBITING OR DOWNREGULATING GLYCOGEN SYNTHASE BY CREATING PREMATURE STOP CODONS USING ANTISENSE OLIGONUCLEOTIDES | GENZYME CORPORATION | 2019-04-25 | — | — | US | disclosed |
| US-20170182171-A1 | MULTIPLE OLIGONUCLEOTIDE MOIETIES ON PEPTIDE CARRIER | GENZYME CORPORATION | 2017-06-29 | — | — | US | disclosed |
| US-20170182189-A1 | INHIBITING OR DOWNREGULATING GLYCOGEN SYNTHASE BY CREATING PREMATURE STOP CODONS USING ANTISENSE OLIGONUCLEOTIDES | GENZYME CORPORATION | 2017-06-29 | — | — | US | disclosed |
| EP-3151841-A1 | MULTIPLE OLIGONUCLEOTIDE MOIETIES ON PEPTIDE CARRIER | Genzyme Corporation (US) | 2017-04-12 | — | — | EP | disclosed |
| EP-3146050-A1 | INHIBITING OR DOWNREGULATING GLYCOGEN SYNTHASE BY CREATING PREMATURE STOP CODONS USING ANTISENSE OLIGONUCLEOTIDES | Genzyme Corporation (US) | 2017-03-29 | — | — | EP | disclosed |
| WO-2015179741-A1 | INHIBITING OR DOWNREGULATING GLYCOGEN SYNTHASE BY CREATING PREMATURE STOP CODONS USING ANTISENSE OLIGONUCLEOTIDES | GENZYME CORPORATION (US) | 2015-11-26 | — | — | WO | disclosed |
| WO-2015179742-A1 | MULTIPLE OLIGONUCLEOTIDE MOIETIES ON PEPTIDE CARRIER | GENZYME CORPORATION (US) | 2015-11-26 | — | — | WO | disclosed |
| WO-2015179743-A1 | LIBRARY AND SCREENING APPROACH FOR IMPROVED CELL PENETRATING PEPTIDES | GENZYME CORPORATION (US) | 2015-11-26 | — | — | WO | disclosed |
| US-5538997-A | HIV PROTEINASE INHIBITORS | SANDOZ LTD. (CH) | 1996-07-23 | — | — | US | disclosed |
| EP-0615969-A1 | 2,4-Diamino-3-hydroxycarboxylic acid derivatives | SANDOZ LTD. (CH) | 1994-09-21 | — | — | EP | disclosed |