Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920128 | 1.00 | HTT (0.52) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL7754003 | 1.00 | HTT (0.52) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL7920125 | 1.00 | HTT (0.52) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL7348249 | 1.00 | HTT (0.52) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL9679074 | 1.00 | HTT (0.52) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL8601689 | 0.98 | HTT (0.48) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL7755361 | 0.98 | HTT (0.48) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL13889961 | 0.91 | TSHR (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL5440335 | 0.91 | TSHR (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL9474466 | 0.91 | TSHR (0.50) | HTTMEN1THRBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153589-A | FOR TREATING VIRAL INFECTIONS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2000-11-28 | — | — | US | disclosed |
| US-5190969-A | Epoxy derivatives of amino acids as viricides for treatment of HIV infections | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 1993-03-02 | — | — | US | disclosed |