Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 19/20 | 0.75 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.75 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.75 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.75 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL733101 | 0.89 | PIK3CD (0.80) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL360745 | 0.85 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL29358478 | 0.85 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL29676506 | 0.85 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL733525 | 0.83 | PIK3CD (0.73) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL733536 | 0.82 | PIK3CD (0.77) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL10307713 | 0.82 | PIK3CD (0.77) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL733871 | 0.81 | PIK3CD (0.69) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL6519357 | 0.80 | PIK3CD (0.87) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL734208 | 0.80 | PIK3CD (0.88) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138195-B2 | Inhibitors of human phosphatidylinositol 3-kinase delta | ICOS CORPORATION (US) | 2012-03-20 | — | — | US | claimed |