Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29434852 | 0.78 | CYP1A2 (1.00) | MEN1CYP1A2KMT2ACYP2C19CA2 | |
| SCHEMBL7370655 | 0.78 | CYP1A2 (1.00) | MEN1CYP1A2KMT2ACYP2C19CA2 | |
| SCHEMBL13038637 | 0.78 | MEN1 (0.59) | MEN1CYP1A2KMT2ACYP2C19 | |
| SCHEMBL2451041 | 0.76 | CYP1A2 (0.57) | MEN1CYP1A2KMT2ACYP2C19GRM1 | |
| SCHEMBL2451043 | 0.76 | CYP1A2 (0.57) | MEN1CYP1A2KMT2ACYP2C19GRM1 | |
| SCHEMBL25205790 | 0.74 | SRD5A2 (0.53) | MEN1CYP1A2KMT2ATSHRTP53 | |
| SCHEMBL21112142 | 0.71 | MEN1 (0.51) | MEN1CYP1A2KMT2ACYP2C19KIF11 | |
| SCHEMBL21112143 | 0.71 | MEN1 (0.51) | MEN1CYP1A2KMT2ACYP2C19KIF11 | |
| SCHEMBL13956160 | 0.71 | KCNN4 (0.61) | MEN1CYP1A2KMT2AGRM5GRM1 | |
| SCHEMBL28645834 | 0.70 | KMT2A (0.50) | MEN1CYP1A2KMT2ACYP2C19KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997021715-A1 | ALPHA-CYCLOPROPYL-SUBSTITUTED PHENYLGLYCINES AS CNS AGENTS | UNIVERSITY OF BRISTOL (GB) | 1997-06-19 | — | — | WO | disclosed |