Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20969564 | 0.80 | PARP15 (0.51) | PARP10PARP15FNTAFNTBPARP2 | |
| SCHEMBL20969685 | 0.75 | PARP15 (0.50) | PARP10PARP15FNTAFNTBPARP2 | |
| SCHEMBL3423612 | 0.73 | PARP10 (0.58) | PARP10PARP15FNTAFNTBPARP2 | |
| SCHEMBL7463070 | 0.73 | MAPT (0.57) | HPGDNPC1RAB9A | |
| SCHEMBL4427324 | 0.73 | PARP10 (0.51) | PARP10PARP15FNTAFNTBPARP2 | |
| SCHEMBL22192683 | 0.72 | PARP15 (0.65) | PARP10PARP15FNTAFNTBPARP2 | |
| SCHEMBL4573802 | 0.72 | PARP10 (0.62) | PARP10PARP15FNTAFNTBPARP2 | |
| SCHEMBL24618063 | 0.71 | PARP15 (0.53) | PARP10PARP15FNTAFNTBPARP2 | |
| SCHEMBL20969745 | 0.71 | PARP15 (0.47) | PARP10PARP15PARP2 | |
| SCHEMBL7041912 | 0.71 | PARP10 (0.43) | PARP10PARP15PARP2FFAR1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007689-A1 | ANILINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-02-18 | — | — | WO | claimed |