Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511112 | 0.90 | KMT2A (0.47) | KMT2AHPGDLMNASMN1; SMN2HTT | |
| SCHEMBL11610221 | 0.82 | KMT2A (0.49) | KMT2AHPGDLMNASMN1; SMN2HTT | |
| SCHEMBL3235742 | 0.82 | SMN1; SMN2 (0.47) | KMT2AHPGDLMNASMN1; SMN2HTT | |
| SCHEMBL16299041 | 0.82 | MAPT (0.57) | KMT2ALMNASMN1; SMN2HTTKDM4E | |
| SCHEMBL9729001 | 0.82 | SMN1; SMN2 (0.52) | KMT2AHPGDLMNASMN1; SMN2HTT | |
| SCHEMBL8239030 | 0.80 | HSD17B10 (0.59) | KMT2AHPGDHTTKDM4EMAPT | |
| SCHEMBL15854548 | 0.79 | HDAC8 (0.60) | KMT2AHPGDLMNASMN1; SMN2HTT | |
| SCHEMBL12684764 | 0.79 | HDAC1 (0.60) | KMT2AHPGDLMNASMN1; SMN2HTT | |
| SCHEMBL1519151 | 0.79 | SMN1; SMN2 (0.47) | KMT2AHPGDLMNASMN1; SMN2HTT | |
| SCHEMBL10873524 | 0.79 | IDO1 (0.56) | KMT2AHPGDLMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0598962-B1 | Imidazole derivatives as calcium channel blockers | NEUROSEARCH AS (DK) | 1999-02-17 | — | — | EP | disclosed |
| EP-0598962-A1 | Imidazole derivatives as calcium channel blockers | NEUROSEARCH A/S (DK) | 1994-06-01 | — | — | EP | disclosed |
| US-5296493-A | Analgesics or antiischemics | NEUROSEARCH A/S (DK) | 1994-03-22 | — | — | US | disclosed |