Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.76 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343869 | 0.91 | F2 (0.63) | F2 | |
| SCHEMBL9077188 | 0.91 | F2 (0.63) | F2 | |
| SCHEMBL9075651 | 0.88 | F2 (0.60) | F2F10 | |
| SCHEMBL7348750 | 0.88 | F2 (0.76) | F2F10PLGPLAUST14 | |
| SCHEMBL9075686 | 0.86 | F2 (1.00) | F2 | |
| SCHEMBL9076780 | 0.85 | F2 (1.00) | F2F10 | |
| SCHEMBL8154518 | 0.82 | F2 (1.00) | F2F10 | |
| SCHEMBL7343994 | 0.82 | F2 (0.72) | F2 | |
| SCHEMBL9075817 | 0.82 | F2 (1.00) | F2F10 | |
| SCHEMBL9073858 | 0.82 | F2 (1.00) | F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583146-A | Heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0623595-A1 | Guanidinyl- or amidinyl-substituted heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-11-09 | — | — | EP | disclosed |