Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI2 | P48307 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | PPM1B | O75688 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | PPP1CC | P36873 | 3/20 | 0.44 |
| ▸ | PPP5C | P53041 | 4/20 | 0.42 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.33 |
| ▸ | PPP2CA | P67775 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454894 | 0.88 | TFPI2 (0.54) | TFPI2LMNAKDM4EGMNNPMP22 | |
| SCHEMBL21647281 | 0.78 | TP53 (0.54) | TFPI2LMNAKDM4EGMNNPMP22 | |
| SCHEMBL20656751 | 0.78 | GABRR1 (0.40) | TFPI2LMNAKDM4EGMNNPMP22 | |
| SCHEMBL27831580 | 0.76 | TFPI2 (0.43) | TFPI2LMNAKDM4EGMNNPMP22 | |
| SCHEMBL21436920 | 0.74 | PPM1B (0.53) | PPM1BPTPN1PPP1CC | |
| SCHEMBL28136773 | 0.73 | — | — | |
| SCHEMBL3191742 | 0.72 | TFPI2 (0.74) | TFPI2LMNAKDM4EGMNNPMP22 | |
| SCHEMBL3497096 | 0.72 | TFPI2 (0.74) | TFPI2LMNAKDM4EGMNNPMP22 | |
| SCHEMBL22973670 | 0.70 | PPM1B (0.57) | TSHRPPM1BPTPN1PPP1CCPPP5C | |
| SCHEMBL2806779 | 0.70 | PEPD (0.41) | TFPI2LMNAKDM4EGMNNPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994009005-A1 | 4,7-BRIDGED ISOINDOLES AS ANTIPSYCCHOTIC AND ANTIDYSKINETIC AGENTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-04-28 | — | — | WO | disclosed |