SCHEMBL7350291

SCHEMBL7350291

Cn1cc(C(=O)Cc2ccc(C(=N)N)cc2)c2ccc(N(CC(=O)O)C(=O)c3ccccn3)cc21

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
F2 P00734 17/20 0.44
LMNA P02545 1/20 0.42
F10 P00742 7/20 0.39
SLC22A2 O15244 1/20 0.36
PLG P00747 1/20 0.36
PLAT P00750 1/20 0.36
PROC P04070 1/20 0.36
HPN P05981 1/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
NQO2 P16083 1/20 0.36
PRSS3 P35030 1/20 0.36
SLC47A2 Q86VL8 1/20 0.36
SLC47A1 Q96FL8 1/20 0.36
ITGB3 P05106 4/20 0.35
ITGA2B P08514 4/20 0.35
PLAU P00749 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7360227 0.93 F2 (0.45) F2LMNAF10SLC22A2PLG
Hydrochloric Acid SCHEMBL7350397 0.92 F2 (0.46) F2F10SLC22A2PLGPLAT
Hydrochloric Acid SCHEMBL7355682 0.90 F10 (0.44) F2LMNAF10NQO2ITGB3
SCHEMBL7359069 0.86 F2 (0.44) F2LMNAF10ITGB3ITGA2B
Hydrochloric Acid SCHEMBL7360761 0.83 F2 (0.44) F2LMNAF10NQO2ITGB3
Hydrochloric Acid SCHEMBL7359123 0.82 F2 (0.43) F2F10NQO2ITGB3ITGA2B
Hydrochloric Acid SCHEMBL7352009 0.80 F2 (0.50) F2LMNAF10ITGB3ITGA2B
Hydrochloric Acid SCHEMBL7361275 0.80 F2 (0.46) F2LMNAF10ITGB3ITGA2B
Hydrochloric Acid SCHEMBL7359124 0.79 F2 (0.45) F2LMNAF10ITGB3ITGA2B
Hydrochloric Acid SCHEMBL7354985 0.78 F2 (0.46) F2LMNAF10ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999028297-A1 SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT BOEHRINGER INGELHEIM PHARMA KG (DE) 1999-06-10 WO disclosed