Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 14/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038931 | 0.92 | CACNA1B (0.59) | CACNA1BMEN1KMT2ATP53CYP2D6 | |
| SCHEMBL7038932 | 0.82 | CACNA1B (0.72) | CACNA1BMEN1KMT2A | |
| SCHEMBL7043564 | 0.82 | CACNA1B (0.60) | CACNA1BMEN1KMT2ATP53CYP2D6 | |
| SCHEMBL7043640 | 0.78 | CACNA1B (0.61) | CACNA1BMEN1KMT2ATP53CYP2D6 | |
| SCHEMBL7041777 | 0.78 | CACNA1B (0.60) | CACNA1BMEN1KMT2A | |
| SCHEMBL7043363 | 0.77 | CACNA1B (0.60) | CACNA1BMEN1KMT2A | |
| SCHEMBL7040844 | 0.77 | CACNA1B (0.60) | CACNA1BMEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL7037600 | 0.76 | CACNA1B (0.54) | CACNA1BMEN1KMT2A | |
| SCHEMBL7037026 | 0.75 | CACNA1B (0.62) | CACNA1B | |
| SCHEMBL7040536 | 0.72 | CACNA1B (0.46) | CACNA1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007689-A1 | ANILINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-02-18 | — | — | WO | claimed |