Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | NEK2 | P51955 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL7350589 | 0.91 | HRH3 (0.42) | HRH3HRH4PDE4DBTKCCNC | |
| SCHEMBL7344255 | 0.88 | HRH3 (0.42) | HRH3HRH4PDE4DBTKNEK2 | |
| SCHEMBL27513356 | 0.84 | HRH3 (0.39) | HRH3HRH4PDE4DBTKNEK2 | |
| SCHEMBL27496064 | 0.78 | HRH3 (0.40) | HRH3HRH4PDE4DBTK | |
| SCHEMBL7344262 | 0.78 | HRH3 (0.40) | HRH3HRH4PDE4D | |
| SCHEMBL7341730 | 0.73 | KDM4E (0.35) | KDM4ECYP2C19 | |
| SCHEMBL7342860 | 0.73 | ALK (0.42) | — | |
| SCHEMBL7350171 | 0.73 | HRH4 (0.45) | HRH4KDM4E | |
| SCHEMBL8356693 | 0.72 | HRH3 (0.40) | HRH3HRH4PDE4DBTKNEK2 | |
| SCHEMBL7367195 | 0.72 | PARP1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1219933-A | Novel oxazolidine derivatives, process for their preparation and pharmaceutical preparations containing these compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1999-06-16 | — | — | CN | disclosed |
| EP-0891359-A1 | NOVEL OXAZOLIDINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036899-A1 | NOVEL OXAZOLIDINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1997-10-09 | — | — | WO | disclosed |