⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2600750 | 0.80 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL7350745 | 0.76 | — | — | |
| SCHEMBL13744530 | 0.73 | — | — | |
| SCHEMBL11455599 | 0.71 | — | — | |
| SCHEMBL5564739 | 0.67 | — | — | |
| SCHEMBL27679165 | 0.66 | GAA (0.50) | — | |
| SCHEMBL5565094 | 0.64 | — | — | |
| SCHEMBL11445494 | 0.63 | — | — | |
| SCHEMBL76903 | 0.62 | — | — | |
| SCHEMBL16111692 | 0.62 | GAA (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027332-A1 | NOVEL LACTAM METALLOPROTEASE INHIBITORS | Du Pont Pharmaceuticals Company (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999018074-A1 | NOVEL LACTAM METALLOPROTEASE INHIBITORS | Britol-Myers Squibb Pharma Company (US) | 1999-04-15 | — | — | WO | disclosed |