Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359105 | 0.94 | F2 (0.65) | F2ALDH1A1F10POLBMAPT | |
| Hydrochloric Acid SCHEMBL7358813 | 0.91 | F2 (0.52) | F2ALDH1A1F10POLBMAPT | |
| SCHEMBL8491517 | 0.88 | F2 (0.60) | F2ALDH1A1MAPTEGLN1 | |
| Hydrochloric Acid SCHEMBL7357099 | 0.88 | F2 (0.66) | F2ALDH1A1F10MAPT | |
| Hydrochloric Acid SCHEMBL7356248 | 0.86 | F2 (0.54) | F2ALDH1A1F10POLBMAPT | |
| Hydrochloric Acid SCHEMBL7361185 | 0.83 | F2 (0.66) | F2ALDH1A1F10MAPT | |
| Hydrochloric Acid SCHEMBL7351752 | 0.82 | F2 (0.59) | F2ALDH1A1F10MAPT | |
| Hydrochloric Acid SCHEMBL7352296 | 0.82 | F2 (0.68) | F2ALDH1A1F10MAPT | |
| SCHEMBL8489800 | 0.82 | F2 (0.53) | F2ALDH1A1MAPTEGLN1 | |
| SCHEMBL8525762 | 0.80 | F2 (0.51) | F2ALDH1A1F10KLKB1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |